A 39-year-old female was seen in the dental hygiene clinic for a routine cleaning appointment. During the initial exam, the student noticed this white lesion on her posterior buccal gingiva. The patient had first noticed the lesion several months ago. As far as she could tell, there had been no recent changes in size or appearance.
Intra-oral exam revealed a well-demarcated white lesion on the gingiva below the mandibular canines and premolars. The lesion was approximately 15 x 10 mm in size. The lesion was a little non-homogenized in appearance.
39-year-old female with leukoplakia |
Based on the appearance, this lesion was diagnosed as leukoplakia. A biopsy of the lesion was recommended. The periodontist performed an incisional biopsy. The pathologist felt that the tissue appeared pre-neoplastic under the microscope. The case was signed out as mild epithelial dysplasia. The patient was scheduled for regular follow-ups to monitor changes in size, texture and appearance. If any of these was detected, a re-biopsy was strongly recommended.
For a detailed discussion on leukoplakia, please see post, The Case of a White Lesion.
Oral Dysplasia:
Dysplasia is usually a difficult concept to grasp for clinicians. The best way to describe dysplasia is as "pre-cancer". It is a phase that the epithelial cells go through before invading the underlying connective tissue. According the extent of epithelial involvement, dysplasia is classified as mild, moderate and severe.
It is important to keep in mind that the criteria according to which oral dysplasia is classified is very different than the rest of the body. Oral dysplasia tends to be a lot more subtle. General pathologists are more familiar with cervical dysplasia and try to enforce a similar criteria for oral dysplasia, this usually results is misdiagnosis and delayed intervention.
For a detailed discussion on leukoplakia, please see post, The Case of a White Lesion.
Oral Dysplasia:
Dysplasia is usually a difficult concept to grasp for clinicians. The best way to describe dysplasia is as "pre-cancer". It is a phase that the epithelial cells go through before invading the underlying connective tissue. According the extent of epithelial involvement, dysplasia is classified as mild, moderate and severe.
It is important to keep in mind that the criteria according to which oral dysplasia is classified is very different than the rest of the body. Oral dysplasia tends to be a lot more subtle. General pathologists are more familiar with cervical dysplasia and try to enforce a similar criteria for oral dysplasia, this usually results is misdiagnosis and delayed intervention.
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